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Reference guide

Tirzepatide dosage chart

The standard weekly titration from 2.5 mg to 15 mg, with the context to read it correctly and a calculator to convert to units.

Educational use only. This tool and content are for general information and do not constitute medical advice, diagnosis, or treatment. Peptides and GLP-1 medications should only be used under the supervision of a licensed healthcare provider. Always confirm dosing with your prescriber and the product label. Some peptides discussed are not approved by the FDA for human use.
Tirzepatide weekly titration (mg)Weeks 1–42.5 mgWeeks 5–85 mgWeeks 9–127.5 mgWeeks 13–1610 mgWeeks 17–2012.5 mgWeeks 21+15 mg
Based on FDA prescribing information for tirzepatide (Mounjaro® / Zepbound®).
PhaseWeekly doseTypical duration
Starting2.5 mg4 weeks (non-therapeutic starter)
Step 25 mg4 weeks · first maintenance option
Step 37.5 mg4 weeks
Step 410 mg4 weeks
Step 512.5 mg4 weeks
Maximum15 mgMaintenance

The 2.5 mg starting dose is designed to ease your gut into the medication, not to drive weight loss. Most people increase every four weeks only as side effects allow, and many settle at a maintenance dose between 5 and 15 mg.

Convert mg to units

Use the tirzepatide dosage calculator to convert any dose to exact units for your vial and BAC water.

Get tirzepatide with a licensed provider

A prescription matters: real reconstitution should be done with pharmacy-grade product and clinician guidance. These telehealth services handle the evaluation, prescription, and shipping.

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Frequently asked questions

How long do you stay on each tirzepatide dose?
Typically four weeks per step before considering an increase, though your clinician may move slower if you have side effects.
Do you have to reach 15 mg?
No. The right dose is the lowest one that controls appetite and maintains your results. Many people never go above 10 mg.

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